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Hypoglycemia 🫤🫤

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Hypoglycemia 🫤🫤

When blood glucose level is bellow 3.5 mmol/L then it is called hypoglycemia. It occurs in a patient who is treated by insulin or sulphonylurea and not a manifestation of the disease itself. 

Causes of Hypoglycemia :

  1. Missed, delayed or inadequate meal 
  2. Unexpected or unusual exercise 
  3.  Alcohol 
  4.  Errors in oral hypoglycemic agent or insulin dose /schedule /administration 
  5. Poorly designed insulin regimen, particularly if predisposing to nocturnal hyperinsulinaemia
  6.  Lipohypertrophy at injection sites causing variable insulin absorption 
  7.  Gastroparesis due to autonomic neuropathy 
  8. Malabsorption, eg. Celiac disease 
  9. Unrecognized other endocrine disorder, eg. Addison's disease 
  10. Factitious 

 Breastfeeding by diabetic mother


Risk factors of severe hypoglycemia :

1. Strict glycemic control 

2. Impaired awarenesses of hypoglycemia 

3. Age (very young and elderly) 

4. Increasing duration of diabetes 

5. Sleep 

6. C-peptic negativity

7. History of previous hypoglycemia 

8. Renal impairment 

9. Angiotensin converting enzyme (ACE) genotype 



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